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Pharmacological Action: Emacardin properties are attributed to Hawthorn content of flavonoids and procyanidins. Emacardin action is mediated through phosphodiesterase inhibition leading to increase in intracellular CAMP and increased calcium membrane permeability, leading to vasodilation, increased coronary blood flow, and positive inotropic effect. Emacardin improves myocardial tissue perfusion, reduces peripheral resistance and improves exercise tolerance in cardiac patients. |